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Neuroscience Jeopardy

Neurons, neurotransmitters, brain regions, and memory on a free intro neuroscience board. Project it for review and let everyone buzz in from phones.

6 categories · 30 clues · Final Jeopardy · everyone buzzes in from their phone

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The Neuron

  1. $200

    These branching extensions of a neuron receive most of its incoming signals from other cells.

    What are dendrites?

  2. $400

    This fatty insulating layer wraps many axons and is made by oligodendrocytes in the central nervous system.

    What is myelin?

  3. $600

    These star-shaped glial cells help maintain the blood-brain barrier and regulate extracellular potassium.

    What are astrocytes?

  4. $800

    This cone-shaped region where the axon leaves the cell body is where action potentials are typically triggered.

    What is the axon hillock?

  5. $1,000

    Using Golgi's silver stain, this Spanish scientist argued that neurons are discrete cells, the heart of the neuron doctrine.

    Who was Santiago Ramón y Cajal?

Action Potentials

  1. $200

    This ion rushes into the neuron through voltage-gated channels during the rising phase of an action potential.

    What is sodium?

  2. $400

    This ATP-driven membrane pump moves three ions out of the cell for every two it brings in.

    What is the sodium-potassium pump?

  3. $600

    Reaching this membrane potential, often around -55 millivolts, triggers an all-or-none action potential.

    What is the threshold?

  4. $800

    This form of conduction lets impulses leap from one node of Ranvier to the next along myelinated axons.

    What is saltatory conduction?

  5. $1,000

    Alan Hodgkin and Andrew Huxley worked out the ionic basis of the action potential using the giant axon of this animal.

    What is the squid?

Neurotransmitters

  1. $200

    Loss of neurons releasing this neurotransmitter in the substantia nigra causes the motor symptoms of Parkinson's disease.

    What is dopamine?

  2. $400

    This is the main inhibitory neurotransmitter in the adult brain.

    What is GABA?

  3. $600

    Released at every vertebrate neuromuscular junction, this was the first neurotransmitter ever identified.

    What is acetylcholine?

  4. $800

    Prozac and other SSRIs block the reuptake of this neurotransmitter.

    What is serotonin?

  5. $1,000

    This most abundant excitatory neurotransmitter acts on NMDA and AMPA receptors.

    What is glutamate?

Brain Anatomy

  1. $200

    This structure at the back of the brain, whose name means little brain, coordinates balance and fine motor control.

    What is the cerebellum?

  2. $400

    This thick band of axons connects the left and right cerebral hemispheres.

    What is the corpus callosum?

  3. $600

    This small structure controls the pituitary gland and regulates hunger, thirst and body temperature.

    What is the hypothalamus?

  4. $800

    Damage to this region of the left frontal lobe produces halting, effortful speech with relatively spared comprehension.

    What is Broca's area?

  5. $1,000

    This ridge of cortex just behind the central sulcus houses the primary somatosensory cortex.

    What is the postcentral gyrus?

Sensation and Movement

  1. $200

    These retinal photoreceptors handle color vision and work best in bright light.

    What are cones?

  2. $400

    This spiral-shaped structure of the inner ear converts sound vibrations into neural signals.

    What is the cochlea?

  3. $600

    Sensory signals from every sense except smell pass through this relay structure on their way to the cortex.

    What is the thalamus?

  4. $800

    These neurons carry commands from the brainstem and spinal cord directly to skeletal muscle fibers.

    What are lower motor neurons?

  5. $1,000

    This sense of the body's position in space relies on receptors in muscles, tendons and joints.

    What is proprioception?

Learning and Memory

  1. $200

    This Russian physiologist's dogs learned to salivate at a sound that predicted food.

    Who was Ivan Pavlov?

  2. $400

    Riding a bicycle relies on this kind of implicit memory for skills and habits.

    What is procedural memory?

  3. $600

    This almond-shaped structure in the temporal lobe is essential for learning to fear a tone paired with a shock.

    What is the amygdala?

  4. $800

    This lasting strengthening of synapses after high-frequency stimulation is a leading cellular model of memory.

    What is long-term potentiation?

  5. $1,000

    Eric Kandel shared a Nobel Prize for work on the cellular basis of memory in this sea slug.

    What is Aplysia?

Final Jeopardy — Famous Patients

Patient H.M. lost the ability to form new long-term memories after 1953 surgery removed much of both medial temporal lobes, revealing the role of this seahorse-shaped structure.

What is the hippocampus?

How to run this board

The board covers the core of an intro neuroscience or biopsychology course: neuron structure, action potentials, synapses and neurotransmitters, brain anatomy, sensory and motor systems, and learning and memory, including the classic patient cases.

Anatomy clues stick better with a picture, so keep a labeled brain diagram ready and point to the region after each answer. For the action potential column, ask the answering team which ion is moving and in which direction for a bonus.

Lab groups make natural teams. Keep a list of the clues nobody got - they are a ready-made study list for the exam.

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